Strain-dependent differences in murine susceptibility to toxoplasma

Mouse strain-dependent differences in susceptibility to Neisseria gonorrhoeae infection and induction of innate immune responses.

Acute gonorrhea in women is characterized by a mucopurulent exudate that contains polymorphonuclear leukocytes (PMNs) with intracellular gonococci. Asymptomatic infections are also common. Information on the innate response to Neisseria gonorrhoeae in women is limited to studies with cultured cells, isolated immune cells, and analyses of cervicovaginal fluids. 17beta-Estradiol-treated BALB/c mi...

Evaluation of gender-related differences in response to oxidative stress in toxoplasma gondii positive serum

  Purpose: Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis. It infects up   to one third of the human population. The aim of this study was to evaluate the effects of T.   gondii infection on induction of oxidative stress in serum of infected men and women.   Materials and Methods: This case-control study was carried out on 150 individuals who had   referred to our center ...

Strain differences influence murine pulmonary responses to Stachybotrys chartarum.

When the fungus Stachybotrys chartarum is inhaled, its mycotoxins may cause lung injury and inflammation. The severity of human responses to S. chartarum in both occupational and home settings varies widely. To explore these differences, we intratracheally instilled C3H/HeJ, BALB/c, and C57BL/6J mice with S. chartarum spores suspended in saline. One day later, the mice were humanely killed, bro...

Strain-dependent differences in host response to Candida albicans infection in mice are related to organ susceptibility and infectious load.

After systemic infection with the yeast Candida albicans, inbred mice show substantial differences in mortality, organ colonization, and severity of tissue damage. To examine the relationships between these variables, which are not directly correlated with each other, fungal colonization of the kidneys and brain was enumerated in six inbred strains that exhibit different patterns of tissue dama...

Infection: An Arginase-Dependent Effect Mouse Strain Susceptibility to Trypanosome